Caritas Pakistan Karachi has been established as a diocesan office in 1965 in Archdiocese of Karachi, under the leadership of late Cardinal Joseph Cordeiro. In the early days, the office of Caritas Pakistan Karachi was established on Shahrah-e-Iraq, which remained there until 1996. Initially, Caritas Pakistan office was established on Shahra-e-Iraq in Saddar Karachi. In 1997 Caritas Karachi office was shifted new place at 57/W Block 6, PECHS, Karachi.